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Prednisone or another corticosteroid can prevent blindness when it is used to calm acute inflammation of blood vessels in the head, called giant cell arteritis. But the medication doesn't appear to prevent sudden death, even when the disease is so severe that people with the disease die within a few hours of having it. The authors caution that their study only showed an association between corticosteroids and sudden death. Corticosteroids don't seem to be responsible for the number of deaths. Another way to make sure you avoid sudden-death syndrome is to get screened for it by getting a blood test for the hormone chorionic gonadotropin, which is released from the ovaries, which is an indicator of early pregnancy, said Linda L. Nader, a professor of obstetrics, gynecology and reproductive sciences and senior author of the study in the Journal of Pregnancy and Childbirth. The hormone causes the placenta to produce new blood around the time of delivery. Although these tests can prevent sudden-death syndrome in pregnancy, they don't provide any guarantee, said Thomas V. Prentice, a professor of pediatrics, pediatrics-family practice and obstetrics and gynecology at Georgetown University Health System. The tests are still controversial, especially because they aren't very accurate for detecting the syndrome, he said. Corticosteroids have become a "one-way" drug for early pregnancy, Prentice said. It's no longer possible to stop a woman's fertility during delivery so the woman can get a second chance, which would be "a reasonable thing to do," Prentice said. But if a woman took her medication for only a few weeks after delivery, and has a baby and later stops taking her medication, it wasn't clear if the woman's condition would have improved because her body might have released more blood, Prentice said. But this study suggests it may have, so it's important to get a blood test every few months, he said. "You can't predict or prepare," he said. Larissa K. Ritchie, an independent researcher who co-wrote a commentary appearing in the same journal on the same studies, said the studies do suggest a lack of certainty about the relationship between corticosteroid use during pregnancy and the risk of sudden death. But she also pointed out that "no amount of medication is going to give you instant assurance that something bad isn't going to happen." In light of this new study, Ritchie wrote, there is no way to take away the risks of an intervention that only Related Article:

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